Which tissues are typically involved in full-thickness wounds?

• A. Epidermis only.
• B. Subcutaneous tissue only.
• C. Deeper tissues such as muscle or bone.
• D. Hair follicles and sweat glands.

Answer: (C)

Full-thickness wounds involve a depth that passes through both the epidermis and dermis and then extends into deeper tissues such as subcutaneous tissue, muscle, or even bone. The defining point is that the injury goes beyond the surface skin to involve structures beneath, which is why deeper tissues like muscle or bone are typically involved. Wounds limited to the epidermis are superficial and heal by reepithelialization, while a wound described as subcutaneous tissue involvement would already require the dermis to be breached, not just the fat beneath. Hair follicles and sweat glands lie within the dermis and would be affected when the skin’s full thickness is breached, but the key distinction for full-thickness wounds is the involvement of deeper tissues such as muscle or bone.