What is the clinical significance of granulation tissue?

• A. It is red tissue that indicates the wound is healing
• B. It is yellow tissue indicating infection
• C. It is white tissue indicating scarring
• D. It is black tissue indicating necrosis

Answer: (A)

Granulation tissue signifies active wound healing. It’s the pink-reddish tissue formed during the proliferative phase that contains new capillaries, fibroblasts, and extracellular matrix. This vascular, moist tissue shows the wound is progressing toward repair and can bleed easily when touched, reflecting ongoing neovascularization and tissue formation. It helps distinguish healing progress from complications: pale, yellow slough would indicate nonviable tissue or infection, white tissue suggests scar formation, and black tissue points to necrosis. So the presence of granulation tissue is a positive sign that healing is advancing.